Science

ORCID: 0000-0002-5831-5158

Psilocybin

Could psilocybin (a mushroom psychedelic) be used for treating depression? And how does it work?

I’m trying to figure that out at Translational Neuropsychiatry Unit (TNU) in Aarhus as a research year student, investigating the antidepressive effect and molecular mechanisms of psilocybin.

We recently published this article in Acta Neuropsychiatrica, showing that psilocybin lacks an antidepressant-like effect in the Flinders Sensitive Line, a genetic rat model of depression. This doesn’t have to mean that psilocybin cannot have an antidepressant effect, but rather that a different animal model would be better for studying psilocybin.

Systematic reviews of preclinical research is another field I’m involved in – ask me anything.

If you have any inquiries, please write me at oskar.jefsen@clin.au.dk